University of Macau develops AI platform to support TCM drug discovery for Alzheimer’s disease
source:University of Macau 2026-04-27
A research team led by Lu Jiahong, deputy director of the Institute of Chinese Medical Sciences (ICMS) at the University of Macau (UM), in collaboration with Hangzhou MindRank AI Technology Co Ltd and Imperial College London in the UK, has developed an AI platform that integrates a million-compound library and multiple predictive modules for the discovery of bioactive ingredients in traditional Chinese medicine (TCM) and natural products. The team used the platform for virtual screening, followed by cross-species experimental validation, to identify small-molecule TCM compounds with therapeutic potential for Alzheimer’s disease (AD). The findings have been published in the top-tier international journal Nature Biomedical Engineering.